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    July 13

    In Pursuit of the gene: making genetics history

    当我想要准备在space上给写关于这本书的文字的时候,nature 六月28号的nature的读书评论上发表了一篇芝加哥大学生态进化系的Jerry A Coyne教授发表的读书评论。所以,我想先zz一些他的评论在这里,看看他是怎么看这本书的: “when I was a student, "doing genetics" meant crossing two different strains or species. Now it means sequencing DNA, preferably human. Between the two, a pathway fraught with sharp turns, steep gradients and dead ends-and engagingly recounted in James Schwartz's new book. " 这本新书讲的是一些旧的故事。一些告诉我们”基因是什么“ ”基因怎么样工作“ “为什么那时侯他们有一些人如此狂热的相信基因,一个他们根本就不知道是什么化学物质的东西” 而正是这种类似信仰的狂热促成了后来的“doube helex和分子生物学” Jerry A Coyne教授认为书中最高潮的故事是Medal War这一部分:19世纪生物学的两个大发现: 达尔文的进化论,和孟德尔的遗传理论。 虽然我们现在或多或少的都理解达尔文的进化论,也明白孟德尔的豌豆实验做的都是些什么,并且不认为他们两家都有一些什么内在的矛盾到达了不可调和的程度。但是书中对这场“战争”的描述的确是惨烈的。“friendship were destryed, careers threatened" . 而我个人最喜欢是另一个小部分(也许不是小部分,是一个大部分)。Jerry 说的是“immense contribution", 我一点都不觉得过。发生在哥大的fly room里面的Morgan和他的三个学生之间的故事带来的不只是果蝇遗传学的历史。Jerry把Schwartz过分的描述Muller的天才看成是整本书的漏洞,认为他是受了Muller自传的影响。我看完了关于fly room和muller的所有章节: 一个在Morgan反对孟德尔理论的情况下,做出改变Morgan看法的实验的人;一个在受到排挤,在各个大学轮转还能用精彩的实验和推理把一个看成是“反孟德尔基因”理论的最后一个实例变成“孟德尔理论”的又一个证据的人。 “一个第一次提出遗传学要研究基因的分子本质,最好是用bacterial-phage的人” 怎么样的评价和描述,给我带来的都是醍醐灌顶一样的教诲。

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    dawnywrote:
    Jerry 同学实验室现在还在做cross, 哈哈。
     
    话说我们系还有一个人叫 tom,他们就组成 tom and jerry  :)
     
     
    July 15

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